For a better, Microbiome-friendly world!

MyMicrobiome Standard 24.10 tests products for the nose

We breathe in 7,000 liters of air every day, putting our upper respiratory tract in constant contact with our environment. With every gulp of air comes 104 to 106 bacteria per day.

The nose performs important tasks such as filtering, warming and humidifying the inhaled air. In addition, the nose has an olfactory function—we smell our surroundings—but it also has immunological functions such as recognizing pathogenic bacteria.

Nose microbiome

The structure of the upper respiratory tract is relatively complicated and so is the microbiome located there. The typical key bacteria found in the nose are:

Moraxella catarrhalis

Moraxella catarrhalis

Staphylococcus epidermidis

Staphylococcus epidermidis

Propionibacterium acnes

Propionibacterium acnes

Corynebacterium striatum

Corynebacterium striatum

The test criteria for Standard 24.10 nasal mucosa

The product is subjected to four test runs as part of the "Microbiome-friendly" certification.

1. Quality test

It guarantees the greatest possible microbiological purity of the nasal care product. The product is first checked for contamination by mesophilic and aerobic microorganisms, i.e. bacteria, yeast or mold (TAMC and TYMC). For products designed for the nose, the limit is ≤ 1 x 10 2 cfu/g or ml a .

2. Balance test

The balance between the commensal bacteria S. epidermidis and the harmful bacteria S. aureus should not be disturbed by the nasal care product. A co-culture consisting of both germs is mixed with the product for a certain period of time and then the ratio of the two microbes is compared to an untreated control group. Under the influence of the care product, this must not shift in favor of S. aureus.

3. Diversity test

In this step, we cultivate the key microbes common to the nose. For the 24.10 standard, these are Moraxella catarrhalis, Staphylococcus epidermidis, Propionibacterium acnes, Corynebacterium striatum.

A co-culture of all germs is mixed with the product to be tested and the change in diversity is compared with the untreated control group. The diversity of the nasal microbiome must be preserved with regard to the most important key microbes.

4. Vitality test

A Microbiome-friendly product for the nose should not only preserve diversity, but it should also not prove detrimental to the growth of microbes. The test simulates skin contact using a model. Each key microbe is brought into direct contact with the product. This is followed by an additional run during which the microbe is covered with an agar layer and the care product to be tested is applied to it. This process simulates the potential penetration of the product into deeper mucosal layers. The microbial growth of the two batches is compared with the untreated control group, and the growth must not be significantly inhibited.

Dr. Kristin Neumann MyMicrobiome

 

"Products tested in accordance with the 24.10 Standard respect the nasal microbiome. An intact microbial balance in the nose leaves no room for pathogenic (disease-causing) germs to colonize and infect the upper respiratory tract."

Dr. Kristin Neumann, Co-Founder and Chief Scientific Officer

A selection of our customers / awards

Numerous brands from the cosmetics industry with more than 300 tested products trust our seal:

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